发明名称 1-(4-(2-PHENETHYLOXYETHOXY)PHENOXY)-3-(BRANCHEDALKYL)-AMINOPRPAN-2-OLS
摘要 Substituted phenoxy-aminopropanols of the formula <IMAGE> I wherein R is a branched-chain alkyl of 3 or 4 carbon atoms, R1 is hydrogen, halogen or lower alkyl and R2 and R3, independently, are hydrogen, halogen, lower alkyl, lower alkoxy or lower alkylthio, and pharmaceutically acceptable acid addition salts thereof, are described. A process for their preparation, as well as pharmaceutical preparations containing them are also described. The compounds of formula I and their salts possess cardioselective beta -adrenergic blocking activity and antihypertensive activity.
申请公布号 NZ197184(A) 申请公布日期 1984.05.31
申请号 NZ19810197184 申请日期 1981.05.25
申请人 F. HOFFMANN-LA ROCHE & CO. A.G. 发明人 MACHIN P.J.
分类号 C07C217/34;A61K31/135;A61K31/138;A61P9/00;A61P9/06;A61P9/12;C07C29/147;C07C43/178;C07C43/20;C07C43/23;C07C45/71;C07C49/84;C07C59/66;C07C215/00;C07C215/02;C07D303/24;(IPC1-7):07C91/;07C93/;07C43/;07C49/;07D303/;61K31/135;07C149/ 主分类号 C07C217/34
代理机构 代理人
主权项
地址