发明名称 |
LIVE VACCINE FOR BOVINE BABESIOSIS AND METHOD OF PREPARATION |
摘要 |
A live vaccine for bovine babesiosis comprises viable bovine erythrocytes parasitized with a cloned population of Babesia bovis, the clone strain being fast-growing, avirulent, and producing a mild but immunizing infection when administered. The vaccine in free of slow-growing virulent B. bovis. The clone strain used in the vaccine is prepared from a natural mixture of virulent and avirulent babesia by progressive dilution culturing to obtain cultures containing single parasites, propagating the single parasites under favorable conditions for growth, and selecting a fast-growing avirulent clone line for either in vitro or in vivo propagation to prepare tha vaccines. |
申请公布号 |
AU2203783(A) |
申请公布日期 |
1984.05.22 |
申请号 |
AU19830022037 |
申请日期 |
1983.10.18 |
申请人 |
THE CURATORS OF THE UNIVERSITY OF MISSOURI |
发明人 |
BUENING, GERALD MATHEW;CARSON, CHARLES ANDREW |
分类号 |
A61K39/018;C12N1/10;C12R1/91 |
主分类号 |
A61K39/018 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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