| 摘要 |
1,225,830. Anti-psoriasis compositions. CIBA Ltd. 31 Dec., 1968 [8 Jan., 1968], No. 61909/ 68. Heading A5B. Pharmaceutical preparations, e.g. ointments, creams, pastes, foams, lotions and aerosol sprays, for the treatment of psoriasis, contain a dermatologically active steroid, and a triester of dithranol (1,8,9-trihydroxyanthracene) with a C 1-6 alkanoic acid unsubstituted or substituted by halogen and/or C 1-6 alkyl, in admixture or conjunction with a pharmaceutically suitable carrier. Triacetyldithranol is preferred. Suitable steroids include hydrocortisone, prednisolone, fluocortolone, fluorohydrocortisone, dexamethasone, betamethasone, triamcinoline and its acetonide, fluorometholone, 3, 20-dioxo- 6-fluoro-11, 16, 17, 21-tetrahydroxypregna-#<SP>4</SP>- en-16, 17-acetonide, fluocinolone acetonide and flumethasone or their esters with alkanecarboxylic acids or with inorganic acids, e.g. phosphoric or sulpuric acid, such as flumethasone pivalate. The preparations may also contain a keratolytic, e.g. salicyclic acid, antibiotics, antimycotics or antiseptics.
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