发明名称 AMINOCYCLOPENTANONE AMIDES AND PHARMACEUTICAL COMPOSITIONS
摘要 Compounds are described of the formula <IMAGE> (1) in which R1 is unsubstituted or substituted phenylalkyl, thienylalkyl or naphthylalkyl, or cinnamyl; R2 is a hydrogen atom, methyl or alkyl substituted by alkoxy or -COOH; W is alkylene; X is cis or trans -CH=CH- or -CH2CH2-; and Y is a saturated heterocyclic amino group having 5-8 ring members; and their salts and solvates. These compounds inhibit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic and anti-asthmatic agents.
申请公布号 NZ197610(A) 申请公布日期 1984.04.27
申请号 NZ19810197610 申请日期 1981.07.03
申请人 GLAXO GROUP LTD.;HALLETT P. 发明人 COLLINGTON E.W.;WALLIS C.J.;HAYES N.F.
分类号 C07D295/14;A61K31/4433;A61K31/445;A61K31/535;A61K31/5375;A61K31/55;A61P7/02;A61P11/08;A61P43/00;C07C17/16;C07C29/147;C07C67/00;C07C401/00;C07C405/00;C07D267/10;C07D267/20;C07D295/116;C07D295/155;C07D307/935;C07D309/12;C07D311/00;C07D333/12;C07D333/16;C07D333/22;C07D407/12;C07D409/12;C07D413/12;C07D413/14;(IPC1-7):07D295/;07C177/;61K31/557 主分类号 C07D295/14
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