发明名称 |
ACYL PEPTIDES AND PHARMACEUTICAL PREPARATIONS THEREOF, AS WELL AS THEIR MANUFACTURE AND USE |
摘要 |
Acylpeptides derived from somatostatin or from a derivative thereof having analogous action, in which the amino acids sequence is modified by omitting individual amino acids and/or by exchanging them for other amino acids, and in which the epsilon -amino group of the lysine residue in the 9-position, and optionally also the epsilon -amino group of the lysine residue in the 4-position and/or the N-terminal alpha -amino group carries the acyl radical of an optionally substituted alkanecarboxylic acid, and salts and complexes thereof can be used as antidiabetics and/or for combating gastrointestinal bleeding. They are manufactured by conventional methods of peptide chemistry. |
申请公布号 |
DE3066654(D1) |
申请公布日期 |
1984.03.22 |
申请号 |
DE19803066654 |
申请日期 |
1980.12.08 |
申请人 |
CIBA-GEIGY AG |
发明人 |
RINK, HANS;SIEBER, PETER;KAMBER, BRUNO, DR. |
分类号 |
C07K14/575;A61K38/00;A61K38/04;A61P43/00;C07C67/00;C07C231/00;C07C231/02;C07K1/06;C07K1/107;C07K1/113;C07K7/00;C07K14/655;(IPC1-7):C07C103/52;A61K37/02 |
主分类号 |
C07K14/575 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|