| 发明名称 |
Stabilized estradiol cream composition |
| 摘要 |
Loss of potency of estradiol cream compositions found to be due to unexpected oxidation of estradiol. Improved cream composition comprises 1% or less 17 beta -estradiol in the presence of stabilizing members selected from phenolic-type antioxidants, metal chelating agents, and suspending agents.
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| 申请公布号 |
US4436738(A) |
申请公布日期 |
1984.03.13 |
| 申请号 |
US19820358068 |
申请日期 |
1982.03.15 |
| 申请人 |
MEAD JOHNSON & COMPANY |
发明人 |
BEQUETTE, ROBERT J.;HOBBS, LINDA G.;SCOTT, JOSEPH A. |
| 分类号 |
A61K9/00;A61K31/565;A61K47/00;(IPC1-7):A61K31/56 |
主分类号 |
A61K9/00 |
| 代理机构 |
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| 地址 |
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