摘要 |
The process of the invention is remarkable in that a derivative of the transacrylic acid of formula (I) is reacted in an aqueous solution of ammonia or hydroxylamine in the presence of microbian ammonia-lyase produced by a culture of micro-organisms with such an activity, and the product formed of formula (II) is separated. In these formulae, R1 is a hydrogen atom or an alcoyl, R2 is a hydrogen atom or a hydroxyl and R3 is an aromatic or pseudo-aromatic radical. The products obtained are useful especially in peptide synthesis. |