| 摘要 |
FIELD: medicine; methods for producing biologically active substances with immunoregulatory action; may be used in medicine, veterinary practice and experimental biochemistry. SUBSTANCE: invention is directed to novel, synthetic, biologically active peptide with immunoregulatory action and having the formula: X-A-D-Trp-Y, where A is D-Glu, iD-Glu; X is H or Gly, Ala, Leu, Ile, Val, NVal, Pro, Tyr, Phe, Trp, D-Ala, D-Ile, D-Val, D-NVal, D-Pro, D-Tyr, D-Phe, D-Trp, gamma aminobutyric acid,ϑaminocapric acid; Y is Gly, Ala, Leu, Ile, Val, NVal, Pro, Tyr, Phe, Trp, D-Ala, D-Leu, D-Ile, D-Val, D-NVal, D-Pro, D-Tyr, D-Phe, D-Trp, gamma aminobutyric acid,ϑaminocapric acid, OH or substituted (C<SB>1</SB>-C<SB>3</SB>) amide. Invention is also directed to basically new process for producing substances of peptidic nature. EFFECT: simplified method for producing highly effective peptide with higher yield. 2 tbla |
