Process for preparing 3,5-disubstituted 2-pyridylalkyl amines.

摘要

The invention provides a process for preparing a compound of formula (II):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="32" wi="54" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>and salts thereof where one of R' and R<Sup>2</Sup> is C<Sub>1-4</Sub> alkyl, the other is bromo and n is 3-5 which comprises reacting a compound of formula (III):-
<Chemistry id="chema02" num="0002"><Image id="ia02" he="31" wi="50" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>where one of R<Sup>3</Sup> and R<Sup>4</Sup> is C<Sub>1-4</Sub> alkyl and the other is hydrogen with an electrophilic brominating agent.