N-(PHENYLALKYLAMINO-ALKYL)-DIHYDROISOQUINOLINONES,PHARMACEUTICAL COMPOSITIONS AND METHODS EMPLOYING THEM

摘要

Compounds of the formula wherein R1, R2 and R6, which may be identical to or different from each other, are each hydrogen or lower alkyl; R3 is lower alkoxy; R4 is lower alkoxy or, together with R3, methylenedioxy or ethylenedioxy; R5 is hydrogen, lower alkyl or benzyl; R7 is hydrogen or lower alkoxy; R8 is hydrogen, lower alkoxy or, together with R7, methylenedioxy or ethylenedioxy; M IS 1 OR 2; AND N IS 2 OR 3; AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF. The compounds as well as their salts are useful as antihypertensives and heart rate reducers.