发明名称 PENCILLINS ESTERIFIED WITH BETA-LACTAMASE INHIBITING COMPOUND CONTAINING A BETA LACTAM RING
摘要 The present invention relates to hitherto unknown compounds of the general formula I: <IMAGE> I in which R1 stands for a phenyl, 4-hydroxyphenyl, 1,4-cyclohexadienyl or a 3-thienyl group; R2 represents a primary amino or a carboxy group; R3 is a hydrogen atom, or a lower alkyl, aryl or aralkyl radical, and A stands for a radical of a beta -lactamase inhibitor containing a beta -lactam ring as well as a carboxy group, A being connected via the carboxy group. The present invention provides new compounds useful in the treatment of bacterial infections. The new compounds are in particular strongly active against beta -lactamase producing bacteria.
申请公布号 AU532531(B2) 申请公布日期 1983.10.06
申请号 AU19800055462 申请日期 1980.02.12
申请人 LEO PHARMACEUTICAL PRODUCTS LTD. A/S LOVENS KEMISKE FABRI;PRODUKTIONSAKTIESELSKAB 发明人 WAGN OLE GODTFREDSEN;WELF VON DAEHNE
分类号 A61K31/43;C07D;C07D498/04;C07D499/00;C07D499/21;C07D499/32;C07D499/42;C07D499/64;C07D499/66;C07D499/68;C07D499/70;C07D499/72;C07D499/74;C07D503/00;C07D519/00 主分类号 A61K31/43
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