发明名称 THIADIAZINE, OXADIAZINE AND TRIAZINE DERIVATIVES WHICH POSSESS CARDIOTONIC AND/OR ANTIHYPERTENSIVE ACTIVITY
摘要 Heterocyclic compounds of the formula: <IMAGE> wherein either X is -CR1R2- and Y is -O-, -S- or-NHR3-, wherein R1, R2 and R3, which may be the same or different, each is hydrogen or alkyl of up to 4 carbon atoms; or X is -O-, -S- or -NH- and Y is -CR1R2- wherein R1 and R2 have the meanings stated above; wherein R4 and R5, which may be the same or different, each is hydrogen (but provided that R4 and R5 are not both hydrogen), or each is a group defined in claim 1 which is readily convertible into a carboxy group; processes for their manufacture; and pharmaceutical compositions containing them. The compounds possess cardiotonic and/or antihypertensive activity.
申请公布号 ZA8207641(B) 申请公布日期 1983.09.28
申请号 ZA19820007641 申请日期 1982.10.19
申请人 IMPERIAL CHEMICAL INDUSTRIES PLC 发明人 HARGREAVES RODNEY BRIAN;MCLOUGHLIN BERNARD JOSEPH
分类号 A61K45/06;A61P9/04;A61P9/12;C07D253/06;C07D273/04;C07D285/16;C07D403/10;C07D417/12 主分类号 A61K45/06
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