发明名称 |
A process for purifying human chorionic gonadotropin. |
摘要 |
<p>Crude human chorionic gonadotropin ("HCG") is purified by extracting with a neutral or weakly basic aqueous solution containing a lower aliphatic alcohol and a soluble salt, adding a lower aliphatic alcohol to the extracted solution to form precipitate collection and the precipitates containing high purity HCG. The precipitate can be further purified by dissolving in a buffer solution, contacting the solution with a weak anion exchanger and eluting the exchanger with a solution comprising the said buffer and a salt. </p> |
申请公布号 |
EP0089218(A2) |
申请公布日期 |
1983.09.21 |
申请号 |
EP19830301397 |
申请日期 |
1983.03.14 |
申请人 |
NIHON CHEMICAL RESEARCH KABUSHIKI KAISHA ALSO KNOWN AS JAPAN CHEMICAL RESEARCH CO., LTD |
发明人 |
YUKI, YOSHIKAZU;NISHIMURA, TOYOHIKO;HIRATANI, HAJIME |
分类号 |
A61K35/22;A61K38/24;A61P5/00;C07K1/30;C07K14/435;C07K14/575;C07K14/59;C07K14/61;(IPC1-7):07G15/00 |
主分类号 |
A61K35/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|