FREMGANGSMAADE TIL FREMSTILLING AF BLAATUNGEVACCINE OG FREMGANGSMAADE TIL AT IMMUNISERE DROEVTYGGERE HERMED

摘要

Ruminants, particularly cattle, sheep, and goats, can be protected against bluetongue virus (BTV) infection, particularly International Serotypes IT 10, IT 11, IT 13, and IT 17, by parenteral inoculation with the vaccine of the present invention. The vaccine is prepared by attenuating the individual BTV serotypes in at least thirty serial passages through a continuous cell line not originating from ruminants, in particular the "Vero" cell culture derived from the African Green Monkey.