发明名称 2'-SUBSTITUTED-SPIRO(BENZOFURAN-2(3H),1'-CYCLOALKANES)AND INTERMEDIATES THEREOF,A PROCESS FOR PREPARING SAME,PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AND THEIR USE AS MEDICAMENTS
摘要 2'-Substituted-spiro[benzofuran-2(3H),1'-cyclohexanes] and methods of preparing same are described. On the aromatic portion of the benzofuran ring, there may be a substituent or substituents including halogen, amino, lower-alkyl-substituted amino, lower alkyl, lower alkoxy, hydroxy and nitro. The substituents at the 2-position of the cyclohexane ring are -(CH2)nNR1R2 where n is 0, 1 or 2 and R1 and R2 are each independently hydrogen and alkyl of 1-3 carbons. These compounds are useful as antidepressants and analgesics. Various other compounds which are useful as intermediates for preparing the aforementioned compounds and methods for preparing same are also described.
申请公布号 ZA8207595(B) 申请公布日期 1983.08.31
申请号 ZA19820007595 申请日期 1982.10.18
申请人 HOECHST ROUSSEL PHARMA 发明人 GLAMKOWSKI EDWARD JOSEPH;JONES MICHAEL CURTIS
分类号 A61K31/34;A61P25/04;A61P25/24;A61P25/26;C07C67/00;C07C213/00;C07C215/42;C07C215/64;C07C217/74;C07D307/94 主分类号 A61K31/34
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