发明名称 Azabicyclooctane-carboxylic acids and pharmaceutical compositions containing them and antihypertensive use thereof
摘要 Compounds of the formula <IMAGE> in which A represents a vinylene or dimethylene radical, q is 0 or 1, R is an alkyl radical which can carry an amino group, X represents -S- or -NH-, and R1 is a hydrogen atom or a radical of formula <IMAGE> in which R2 is a hydroxy or alkoxy and R3 is a hydrogen atom or an alkyl, cycloalkylalkyl or phenylalkyl radical each having no more than a total of 8 carbon atoms, or an unsubstituted or substituted alkylthioalkyl radical. These compounds are useful as medicaments, especially anti-hypertensive medicaments.
申请公布号 US4397857(A) 申请公布日期 1983.08.09
申请号 US19810313184 申请日期 1981.10.20
申请人 SCIENCE UNION ET CIE 发明人 VINCENT, MICHEL;REMOND, GEORGES;LAUBIE, MICHEL
分类号 C07D451/06;A61K31/435;A61K38/00;A61P9/00;A61P9/12;A61P43/00;C07D221/02;C07D221/22;C07D223/32;C07D453/06;C07K5/02;(IPC1-7):A61K31/44 主分类号 C07D451/06
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