发明名称 |
N- And carboxyl derivatives of thienamycin |
摘要 |
Disclosed are N-acyl and carboxyl derivatives of the antibiotic thienamycin, which has the following structure: <IMAGE> Such derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such derivatives, pharmaceutical compositions comprising such derivatives and methods of treatment comprising administering such derivatives and compositions when an antibiotic effect is indicated.
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申请公布号 |
US4397861(A) |
申请公布日期 |
1983.08.09 |
申请号 |
US19810321497 |
申请日期 |
1981.11.16 |
申请人 |
MERCK & CO., INC. |
发明人 |
CHRISTENSEN, BURTON G.;HANNAH, JOHN;LEANZA, WILLIAM J.;SHIH, DAVID H. |
分类号 |
C07D477/00;A61K31/397;A61K31/40;A61K31/41;A61K31/415;A61K31/42;A61K31/425;A61K31/44;A61K31/495;A61K31/505;A61K31/675;A61P31/04;C07D205/08;C07D477/20;C07D487/04;C07D498/04;(IPC1-7):C07D487/04 |
主分类号 |
C07D477/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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