发明名称 |
PROCESS FOR THE RESOLUTION OF D,L 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID; A MIXTURE OF THE SALTS OF THESE D AND L ACIDS; A PHARMACEUTICAL COMPOSITION CONTAINING A SALT OF THE D ACID; A SALT OF THE D ACID |
摘要 |
Mixtures of d and 1 2-(6-methoxy-2-naphthyl)propionic acids or soluble salts thereof are resolved with N-R-D-glucamine or salts thereof, where R is alkyl having 2 to 36 carbon atoms or cycloalkyl having 3 to 8 carbon atoms, to yield a product substantially enriched in d 2-(6-methoxy-2-naphthyl)propionic acid; a mixture of the salts of d and 1 2-(6-methoxy-2-naphthyl)propionic acid with N-R-D-glucamine; a salt of d 2-(6-methoxy-2-naphthyl)propionic acid with N-R-D-glucamine and a pharmaceutical composition containing this salt in a pharmaceutically effective amount. |
申请公布号 |
DE3063969(D1) |
申请公布日期 |
1983.08.04 |
申请号 |
DE19803063969 |
申请日期 |
1980.07.04 |
申请人 |
SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED |
发明人 |
HOLTON, PERCY GEORGE |
分类号 |
C07B57/00;A61K31/205;A61P7/02;A61P25/04;A61P29/00;C07C51/487;C07C59/52;C07C59/64;C07C67/00;C07C213/00;C07C215/10;C07C229/34;(IPC1-7):C07C59/64;C07C91/10;C07C91/14;C07C51/48;A61K31/19;C07C89/00;C07C89/04;C07C91/26 |
主分类号 |
C07B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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