PROCESS FOR MAKING 1-(3-BENZYLOXYPHENYL)-1,1-DIMETHYLHEPTANE AND INTERMEDIATES THEREFORE

摘要

A process for preparing 1-(3-benzyloxyphenyl)-1,1-dimethylheptane by reacting 1-(3-benzyloxyphenyl)-1-chloro-1-methylheptane in a solvent at -50 DEG to 10 DEG C with from 1 to 3 molar equivalents of trimethylaluminum. Also included are the novel intermediates 1-(3-benzyloxyphenyl)-1-chloro-1-methylheptane and 1-(3-benzyloxyphenyl)-1-methylheptan-1-ol and their preparation. The title compound is a valuable intermediate in the synthesis of certain analgesic agents.