OXOTHIENOBENZOXEPINS,A METHOD FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

摘要

The invention relates to oxothienobenzoxepin compounds of the formula (I) where X together with the carbon atoms to which it is attached is a thiophene ring; R1 is hydrogen, a straight or branched chain alkyl group having 1 to 5 carbon atoms or a halogen atom; R2 is hydrogen or a straight chain alkyl group having 1 to 5 carbon atoms; and R3 is hydroxyl or where R4 is a straight chain or branched chain alkyl group having 1 to 10 carbon atoms, a phenyl group or a trifluoromethyl group. Methods for preparing the compounds and their use as antiinflammatory and analgesic agents are provided.