发明名称 |
DAUNORUBISIN OCH DOXORUBISIN ANALOGER, DERAS FRAMSTAELLNING OCH BRUK |
摘要 |
<IMAGE> The anthracycline glycosides I (X = H or OH, R1 = H or CH3, R2 = H or OCH3, R3 = H or OCH3, R2 = R3) and their pharmaceutically acceptable acid addition salts have antitumour properties. They are prepared from 4-demothoxy-daunomycinone or 2,3-dimethyl-4-methoxy-daunomycinone by condensation with an appropriate N-protected hexopyranosyl chloride and removal of the protecting group and, in the case X = OH, conversion of the 9-acetyl group to a 9-hydroxyacetyl group. |
申请公布号 |
FI830155(L) |
申请公布日期 |
1983.07.27 |
申请号 |
FI19830000155 |
申请日期 |
1983.01.17 |
申请人 |
FARMITALIA CARLO ERBA S.P.A |
发明人 |
PENCO, SERGIO;FRANCHI, GIULIANO;ARCAMONE, FEDERICO;GASAZZA, ANNA MARIA |
分类号 |
C07H15/24;A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;A61P35/02;C07H15/252 |
主分类号 |
C07H15/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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