| 摘要 |
NEW MATERIAL:2,4-Epivaliolamine shown by the formula or its salt. USE:Useful as alpha-glucosidase inhibitor useful for a drug for hyperglycemia, for various kinds of diseases caused by hyperglycoplasmia, a food additive, and an additive for animal feed. Suppressing the metabolism of carbohydrate. PROCESS:Streptomyces hygroscopicus var. limoneus belonging to the genus streptomyces is cultivated under aerobic conditions, and a compound shown by the formula is obtained in the culture. The physical and chemical properties of the compound are as follows. Appearance: hygroscopic white powder, values of elementary analysis (molecular formula): C7H15NO5.H2O, specific rotatory power:[alpha]<25>D+18.2 deg. (C=1, H2O), solubility: soluble in water, ethanol, etc., slightly soluble or insoluble in ethanol, acetone, etc., color reaction: positive in ninhydrin reaction, and reaction by Greig-Leaback reagent, negative in naphthoresorcinol.sulfuric acid reaction. |
