| 发明名称 |
1-(3,4,5-Trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted piperazine derivatives and a process for the preparation thereof. |
| 摘要 |
<p>1-(3,4,5-Trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted piperazine derivatives represented by general formula (I):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="22" wi="84" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R is a straight- or branched-chain alkyl group having 1 to 6 carbon atoms or a cycloalkyl group having 5 to 7 carbon atoms, and pharmaceutically acceptable acid addition salts thereof are disclosed.</p><p>The 1-(3,4,5-trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted piperazine derivatives are useful as vasodilator agents.</p> |
| 申请公布号 |
EP0083712(A1) |
申请公布日期 |
1983.07.20 |
| 申请号 |
EP19820110662 |
申请日期 |
1982.11.18 |
| 申请人 |
HOKURIKU PHARMACEUTICAL CO.,LTD |
发明人 |
ITHO, YASUO;KATO, HIDEO;KOSHINAKA, EIICHI;OGAWA, NOBUO;KURATA, SAKAE;YAMAGISHI, KAGARI |
| 分类号 |
C07D243/08;A61K31/55;A61P9/08;C07D295/18;C07D295/185;(IPC1-7):07D295/18;61K31/495 |
主分类号 |
C07D243/08 |
| 代理机构 |
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