发明名称 |
DERIVATER AF MORPHOLINYLDAUNORUBICIN OG MORPHOLINYLDOXORUBICIN OG ANALOGE DERAF SAMT FREMGANGSMADE TIL FREMSTILLING DERAF |
摘要 |
A group of new daunorubicin and doxorubicin derivatives is disclosed. These materials have the formula <IMAGE> (I) wherein R is CO-CH3 or CHOH-CH3 in the case of daunorubicin derivatives or CO-CH2OH or CHOH-CH2OH in the case of doxorubicin derivatives; X is O or NH; and A is either a cyano group (CN) or a hydrogen, subject to the limitation that when X is O, A must be a cyano group. When A is hydrogen, these compounds can exist as acid addition salts, as well. Derivatives of these compounds are disclosed as well. |
申请公布号 |
DK332983(D0) |
申请公布日期 |
1983.07.19 |
申请号 |
DK19830003329 |
申请日期 |
1983.07.19 |
申请人 |
*SRI INTERNATIONAL |
发明人 |
CAROL WALKER *MOSHER;GEORGE LOW *TONG;EDWARD MCINTOSH *ACTON |
分类号 |
C07D309/14;A61K;A61K31/35;A61K31/351;A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61K31/7042;A61P35/00;C07C;C07H15/24;C07H15/252;C07H17/00 |
主分类号 |
C07D309/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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