Compounds and methods for changing calcium metabolism within the cells of a mammal

摘要

2-alkyl-5,6-dialkoxy (or 5,6 alkylenedioxy) indenes and indane-1-di- or trialkylammonium salts are useful as calcium antagonists, for example in arrhythmia. The compounds are prepared from the known corresponding 2,5,6-substituted indene-1-dimethylammonium salts by alkylation and/or hydrogenation.