| 发明名称 |
2-(Fluoroalkylthio)substituted penems, processes for preparing them, and pharmaceutical compositions containing them. |
| 摘要 |
<p>Compounds are disclosed having the formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="29" wi="65" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>in which the stereochemistry is 5R, 6S, 8R or 5R, 6R, 8S, A represents a fluoroalkyl group, straight chain or branched chain, with 1 to 3 fluorine atoms on the same carbon atom which is separated from the 2-S atom by at least one carbon atom, and R is hydrogen, a pharmaceutically acceptable cation or a metabolisable ester group.</p><p>The compounds have antibacterial activity.</p> |
| 申请公布号 |
EP0080162(A1) |
申请公布日期 |
1983.06.01 |
| 申请号 |
EP19820110612 |
申请日期 |
1982.11.18 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
GIRIJAVALLABHAN, VIVYOOR MOOPIL;MC COMBIE, STUART WALTER;GANGULY, ASHIT KUMAR;PINTO, PATRICK ANTHONY;VERSACE, RICHARD WILLIAM |
| 分类号 |
C07D499/897;A61K31/43;A61P31/04;C07D205/09;C07D499/86;C07D499/87;C07D499/88;C07F7/18;(IPC1-7):07D499/00;61K31/43 |
主分类号 |
C07D499/897 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
