PROCEDE POUR LA PREPARATION DES DERIVES DE CARBOSTYRYLE

摘要

1. New carbostyril derivatives of general formula see diagramm : EP0003771,P26,F1 wherein W represents a vinylene group (optionally substituted by a methyl group) or the ethylene group, m represents the number 0, 1 or 2, D represents a straight-chained or branched alkylene group with 2 to 6 carbon atoms, whilst there must be at least 2 carbon atoms between the oxygen atom and the SOm group, or a xylylene group, R1 represents a cycloalkyl group with 3 to 6 carbon atoms ; an aryl group with 6 to 10 carbon atoms or an aralkyl group with 7 to 11 carbon atoms, whilst the above-mentioned aromatic nuclei may be monosubstituted by an alkyl group with 1 to 4 carbon atoms, by a hydroxy, methoxy, amino, acetylamino, nitro, carboxyl, cyclohexyl or phenyl group or by a halogen atom and, additionally, the above-mentioned monosubstituted phenyl groups may be mono- or disubstituted by alkyl groups with 1 to 4 carbon atoms and/or by halogen atoms (whilst the substituents of the phenyl nucleus may be identical or different) ; an N-methyl-cyclohexylamino-carbonylmethyl, amino-iminomethylene, pyridyl, pyridylmethyl, furfuryl, benzimidazolyl, benzothiazolyl, pyrimidyl, quinolyl, quinazolin-4-on-yl, 4,5-bis-(p-chlorophenyl)-oxazol-2-yl, pyridyloxide, triazolyl, methyl-pyridyl, methoxy-pyridyl, fluoropyridyl, chloropyridyl, aminopyridyl, acetylaminopyridyl or triphenyl-methyl group, or also a tert. butyl group, if m represents the number 1, and R2 and R3 , which may be identical or different, represent hydrogen or halogen atoms, alkyl groups with 1 to 4 carbon atoms, amino, acetylamino or nitro groups.