摘要 |
<p>The derivatives of 2-pyrrole-acetic acid having the formula: <IMAGE> (I) in which R1 is methyl or ethyl and X is hydrogen or chlorine, have a powerful anti-inflammatory action. These derivatives are prepared from ethyl 3,5-diethoxycarbonyl-4-methyl-2-pyrrole-acetate by alkylation, saponification, esterification, decarboxylation, benzoylation and saponification.</p> |