发明名称 Process for the preparation of morpholine and piperidine derivatives
摘要 The invention relates to an improved process for the preparation of fungicidally active compounds of the formula <IMAGE> wherein R1 and R2 individually are lower alkyl of from 1 to 4 carbons or halo-(lower alkyl) of from 1 to 4 carbons or R1 and R2 together with the carbon to which they are attached form a 3 to 7 membered cycloalkyl ring or lower alkyl-substituted cycloalkyl of from 4 to 9 carbons, R3, R4 and R5 individually are hydrogen or lower alkyl of from 1 to 4 carbons and X is methylene or oxygen, and salts of those compounds which are basic. The improved process comprises the reaction of a compound of the formula, <IMAGE> wherein R3, R4, R5 and X have the significance given hereinabove, with a compound which forms a carbonium ion of the formula <IMAGE> wherein R1 and R2 have the significance as given hereinabove.
申请公布号 US4384116(A) 申请公布日期 1983.05.17
申请号 US19810230196 申请日期 1981.02.02
申请人 HOFFMANN-LA ROCHE INC. 发明人 PFIFFNER, ALBERT
分类号 C07D295/02;A01N43/40;A01N43/84;C07D211/14;C07D265/30;C07D295/023;C07D295/03;(IPC1-7):C07D265/30;C07D295/06 主分类号 C07D295/02
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