发明名称 HIGH-VISCOSITY HYALURONIC ACID PREPARATION
摘要 PURPOSE:The titled preparation that is made by adding a salt of hyaluronic acid to an aqueous solution which has been isotonized physiologically using a non- electrolyte, thus being used to treat arthritis, operation at the camera anterior part and retinal detachment. CONSTITUTION:A salt of hyaluronic acid is added to an aqueous solution that has been isotonized physiologically using a non-electrolyte such as polyhydric alcohol, e.g., glycerol, sugar alcohol such as sorbitol, or saccharide such as glycose to prepare its preparation with a high viscosity of 20,000-200,000 cps. The resultant preparation has the objective level of viscosity with a concentration of 3/4 that of the solution in the physiological saline solution, when a hyaluronic acid of 1,500,000 molecular weight, and with a half concentration, when the hyarulonic acid salt has 500,000 molecular weight. The resultant preparation is jelly and sealed in a glass syringe, preferably subjected to intermittent sterilization.
申请公布号 JPS5857319(A) 申请公布日期 1983.04.05
申请号 JP19810156544 申请日期 1981.09.30
申请人 MIDORI JUJI KK 发明人 OOGUSHI TADAYASU;SUZUKI MINORU;HASEGAWA EIICHI
分类号 A61K9/08;A61K31/715;A61K35/36;A61K35/44;A61K47/10;A61K47/26;A61P27/02 主分类号 A61K9/08
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