发明名称 |
Process for introducing alkyl radicals into carbon chains having a functional group and compounds prepared by said process |
摘要 |
Process for introducing a substituent selected from branched- or straight-chain alkyl radicals having from 1 to 12 carbon atoms, aralkyl or cycloalkyl radicals in which the alkyl moiety has from 1 to 4 carbon atoms, into a carbon chain bearing a stable functional group the said carbon chain having at least one proton in alpha -position in relation to this functional group, process whereby, in a first step, this carbon chain is reacted with a complex base comprising a mixture of alkali metal amide and alkali metal alcoholate suspended in an anhydrous organic solvent to provide temporarily a carbanion, then in a second step this carbanion is reacted in an anhydrous organic solvent with an alkyl, aralkyl or cycloalkyl halide corresponding to the substituent to be introduced.
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申请公布号 |
US4377533(A) |
申请公布日期 |
1983.03.22 |
申请号 |
US19810250852 |
申请日期 |
1981.04.03 |
申请人 |
SANOFI |
发明人 |
BOUISSET, MICHEL;CHIGNAC, MICHEL;GRAIN, CLAUDE;PIGEROL, CHARLES |
分类号 |
C07B37/04;B01J31/02;C07B31/00;C07B37/00;C07B61/00;C07C27/00;C07C51/00;C07C51/353;C07C53/122;C07C53/124;C07C53/126;C07C53/128;C07C67/00;C07C67/343;C07C69/24;C07C231/00;C07C231/12;C07C233/05;C07C253/00;C07C253/30;C07C255/00;C07C255/03;C07C255/33;C07F1/04;(IPC1-7):C07C120/00;C07C121/16 |
主分类号 |
C07B37/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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