| 摘要 |
To activate immobilised living microorganisms for the conversion of steroids, antibiotics and other compounds, peptone, glucose or a mixture of peptone and glucose, advantageously in a concentration of 0.1 to 1.0 % (wt./vol.), is added to the reaction mixture. The microorganism, for example Arthrobacter simplex, can be trapped in a polyacrylamide gel. In the application of the process, for example, cortisol or a derivative thereof is converted into prednisolone or a derivative thereof or a steroid is hydroxylated in the 11 or 16 position or dehydrogenated in the 1 position. |
