发明名称 |
2-(4-AMINOBUTOXY)STILBENES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS |
摘要 |
<p>2-(4-Aminobutoxy) stilbenes having the formula (I): …<CHEM>… wherein R<1> is (1)- …<CHEM>… wherein R<2> and R<3> are each hydrogen or C1-C3 alkyl, (2) -N N-R<4> wherein R<4> is C1-C3 alkyl which may be substituted with hydroxy, or (3) hydroxypiperidino; and …<CHEM>… benzene rings, at least one of which contains one or more substituents selected from halogen, C1-C3 alkyl, C1-C3 alkoxy, …<CHEM>… wherein R<5> and R<6> are each C1-C3 alkyl, nitro and ……R<7>O@- wherein R@ is C1-C3 alkyl, and an acid addition salt thereof, are prepared and found useful as pharmaceutical agents, particularly as anti-convulsants and skeletal muscle relaxants.</p> |
申请公布号 |
EP0024567(B1) |
申请公布日期 |
1983.02.16 |
申请号 |
EP19800104513 |
申请日期 |
1980.07.30 |
申请人 |
MITSUBISHI CHEMICAL INDUSTRIES LIMITED |
发明人 |
KIKUMOTO, RYOJI;TOBE, AKIHIRO;FUKAMI, HARUKAZU;EGAWA, MITSUO;NINOMIYA, KUNIHIRO |
分类号 |
A61K31/13;A61K31/135;A61K31/395;A61P25/08;C07C67/00;C07C213/00;C07C217/18;C07C217/80;C07D211/42;C07D295/08;C07D295/092;(IPC1-7):07C93/06;07D295/08;07D211/40;61K31/13;61K31/495;61K31/445 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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