| 摘要 |
Compounds of the formula <IMAGE> wherein R1 and R2 are hydrogen, lower alkyl or phenyl lower alkyl, R2, R3, R4, R5 and R6 are independently hydrogen, lower alkyl, lower alkenyl, lower alkynyl, aryl, fused aryl-cycloalkyl, aralkyl, cycloalkyl, heterocyclic, substituted lower alkyl, lower alkenyl, and lower alkynyl groups wherein the substituent is hydroxy, alkoxy, halo, amino, alkylamino, mercapto and alkylmercapto groups, and substituted cycloalkyl, aryl and heterocyclic groups in which the substituent is alkyl, hydroxy, alkoxy, hydroxyalkyl, halo, mercapto, alkylmercapto, mercaptoalkyl, haloalkyl, amino, alkylamino, aminoalkyl, nitro, methylenedioxy, and trifluoromethyl; each R8 is lower alkyl, lower alkenyl, lower alkynyl, nitro, amino, alkylamino, dialkylamino, hydroxy, alkoxy, mercapto, alkylmercapto, hydroxyalkyl, mercaptoalkyl, halogen, haloalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalky, sulfonamido, methylenedioxy, or trifluoromethyl, m is an integer from 0 to 2 inclusive; m' is an integer from 1 to 3 inclusive, provided that when m is 0, m' is 2 or 3 and, when m is other than 0, m' is 1 or 2; n is an integer from 0 to 4 inclusive, and salts thereof, especially pharmaceutically acceptable salts with an acid or a base. |
