| 摘要 |
2,4-Disubstituted 6-[3,6-dihydro-1(2H)-pyridyl]pyrimidine-3-oxides of the formula <IMAGE> I wherein R1 is lower alkyl or lower alkoxy-lower alkyl, R2 is hydrogen or -COOR3 wherein R3 is lower alkyl or lower alkoxy-lower alkyl, which are important for the preparation of therapeutically valuable 1,2,5,6-tetrahydropyridyl-substituted 2-oxo-2H-[1,2,4]oxadiazolopyrimidinecarbamates, are described. The foregoing oxides of formula I can be prepared by reacting the corresponding arylsulfonyloxy- or alkylsulfonyl-substituted derivatives with 1,2,5,6-tetrahydropyridine. |
