发明名称 |
ANTI-ARTHRITIC HYDROXYACETIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR MANUFACTURE |
摘要 |
The invention concerns novel hydroxyalkanoic acid derivatives of the formula: <IMAGE> I in which A is a straight or branched chain (2-6C)alkylene, R1 and R2 are independently hydrogen or (1-6C) alkyl, and R3 is hydrogen or (1-6C)alkyl, and when R3 is hydrogen, base-addition salts thereof; and processes for their manufacture. The compounds possess useful anti-arthritic properties and the invention also concerns pharmaceutical compositions of such compounds for use in the treatment of arthritic joint diseases. A representative compound of the invention is 2-{2-[4-(4-chlorophenyl)phenyl]-ethoxy}propionic acid. |
申请公布号 |
DE2964097(D1) |
申请公布日期 |
1982.12.30 |
申请号 |
DE19792964097 |
申请日期 |
1979.07.25 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
EDGE, MICHAEL DEREK |
分类号 |
C07C69/712;A61K31/19;A61K31/215;A61K31/22;A61P29/00;C07C45/46;C07C51/00;C07C51/367;C07C59/66;C07C67/00;C07C69/734;(IPC1-7):07C59/135;61K31/215;61K31/19;07C69/708 |
主分类号 |
C07C69/712 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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