| 摘要 |
<p>A compound of formula (I) or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="53" wi="64" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R<Sup>1</Sup> is phenyl, 4-hydroxy phenyl, 3,4-dihydroxyphenyl, 3,4-diacetoxyphenyl or a 5- or 6- membered heterocyclic ring containing up to three heteroatoms selected from oxygen, sulphur or nitrogen, optionally substituted with hydroxy, amino, halogen or C<Sub>1-6</Sub> alkoxy; and R<Sup>2</Sup> is a sub-group of formula (A):
<Chemistry id="chema02" num="0002"><Image id="ia02" he="9" wi="60" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R<Sup>3</Sup> is an optionally substituted C<Sub>1-10</Sub> alkyl or C<Sub>3-7</Sub> cycloalkyl group; or R<Sup>2</Sup> is a sub-group of formula (B):
<Chemistry id="chema03" num="0003"><Image id="ia03" he="9" wi="61" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R<Sup>4</Sup> is an aryl group, an optionally substituted C<Sub>1-10</Sub> alkyl group or a C<Sub>1-6</Sub> alkyloxy group optionally substituted by an aryl group.</p> |
