| 摘要 |
<p>A compound of formula (III): <CHEM> pharmaceutically acceptable salt, ester amide or bioprecursors thereof, wherein R<1> is optionally substituted aryl, aralkyl, aromatic heterocyclic or aromatic heterocyclylalkyl group, and Z is a naphthyl group, optionally substituted with one or more groups selected from C1-6 alkyl, halogen, hydroxy or trifluoromethyl, or Z is a 5 or 6 membered heterocyclic group containing one or more nitrogen, oxygen or sulphur atoms, with at least one of the hetero- atoms being attached to the same carbon atom as the methylene group, and optionally substituted with C1-6 alkyl, halogen, hydroxy or trifluoromethyl, with the proviso that when R<1> is benzyl and Z is a naphthyl group, the compound of formula (III) is not in the DL-form.</p> |
