| 摘要 |
Anthelmintic benzimidazoles I(R1 = aliph. or arom. hydro carbon; R2 = H. aliph. hydrocarbon; R3, R4 = H, aliph. or cyclic or arom. hydrocarbon) were prepd. by the reaction of ophenylene diamine and compd. III (Rx = H, COOR1; Ry = CH, substituted methylene). Thus, 4.5 g S-methy1-isothiourea sulfate and 3.5 g ethy1 chloroformate were reacted with 4.5 g 1,2-diamino- 4 - (4-methy1-2-ethylamino-5 - thiazoloy1)-benzene to give 2-carboethoxyamino-5(6)-(4-methy1-2-methylamino-5-thiazoloy1)-benzimid azole(m.p. 250-255oC).
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