发明名称 |
AMINOPEPTIDASE DERIVED FROM BACILLUS LICHENIFORMIS AND PROCESS FOR PREPARATION OF NATURAL TYPE PROTEINS |
摘要 |
The present invention relates to a process for removing methionine (Met) residue at N-terminus of proteins specifically. Particularly, the present invention relates to an aminopeptidase which is purified from Bacillus licheniformis removes a methionine residue from N-terminus of peptide and proteins. And the present invention relates to a process for preparing a natural type protein from proteins produced in microorganisms by recombinant DNA technology. Various kinds of natural type proteins such as human growth hormone (HGH) can be prepared massively and easily by the process of the present invention. |
申请公布号 |
CA2282734(C) |
申请公布日期 |
2004.10.19 |
申请号 |
CA19982282734 |
申请日期 |
1998.02.16 |
申请人 |
LG CHEMICAL LTD. |
发明人 |
LEE, YOUNG PHIL;PARK, SOON JAE;KIM, SE HOON;HAN, KYUBOEM;LEE, SEUNG JOO |
分类号 |
C12N15/09;C07K14/61;C12N9/48;C12N15/18;C12N15/57;C12P21/02;(IPC1-7):C12N9/48 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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