| 摘要 |
This invention relates to new monophosphonate compounds of formula X-C6H4-(O)m-(CH2)n-R where R is -PO3Me2, -PO3Et2, -PO3H2 or -PO3Na2, X is a halogen, preferably chlorine, in position o, m or p, preferably in position p; m is 0 or 1; and n is 0, 1, 2, 3, 4, 5 or 6, which possess remarkable activity as hypoglycemic and/or antiatherogenic agents, and are usable in pharmaceutical compositions to alter lipoprotein profiles in favor of high density lipoproteins and to clear cholesterol from various tissues. |
