发明名称 Novel process for the preparation of N,N'-bisacyl hydrazides
摘要 An improved process for the preparation of acyl hydrazides of the formula <IMAGE> I wherein A and B individually are a group of the formula <IMAGE> wherein R1 is selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms, x is 0 or 1 and R2 and R3 are individually selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms and n and m are individually 0, 1, 2 or 3 by reacting a compound of the formula <IMAGE> II with a hydrazide of the formula <IMAGE> III the improvement comprising effecting the reaction in the presence of at least one catalyst selected from the group consisting of amines, amine alkoxides and quaternary ammonium hydroxides.
申请公布号 US4357277(A) 申请公布日期 1982.11.02
申请号 US19810224128 申请日期 1981.01.12
申请人 RUTGERSWERKE AKTIENGESELLSCHAFT 发明人 ORTH, WINFRIED;LANGE, FRITZ W.;FICKERT, WERNER
分类号 A61K31/40;A61K31/4015;A61P25/18;C07D207/26;C07D207/27;(IPC1-7):C07D207/27;C07D211/76;C07D227/00;C07D401/12 主分类号 A61K31/40
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