Tetrahydroisoquinoline compounds, processes for preparation thereof and pharmaceutical composition containing them.

摘要

Novel tetrahydroisoquinoline compounds of the formula: <CHEM> wherein R<1> is lower alkyl or phenyl-lower alkyl, R<2> is alkyl or phenyl-lower alkyl, R<3> is hydrogen or lower alkyl and R<4> is hydrogen, lower alkyl or aralkyl, and pharmaceutically acceptable salts thereof are disclosed. Said compounds (I) and salts thereof are useful as hypotensive agent. There is also described a process for preparation of said compounds as well as pharmaceutical compositions containing same.