| 摘要 |
NEW MATERIAL:A compound of formulaI(R<1>, R<2> are H, lower alkyl, or they incorporate together with adjacent nitrogen atom to form heterocyclic ring; X is >C=O, >CH-OH). EXAMPLE:7-Diethylamino-2, 3, 5, 6,7, 8-hexahydro-[1,4]thiazino[2, 3, 4jk][1] benzoazepin-3,8-dione. USE:Phycotropic, hypotensor, analgesic or circulation improver: it has central, hypotensive, or analgesic actions. PREPARATION:The reaction of a compound of formula II (Z is halogen such as Br, Cl) with another compound of formula III gives a compound of formula Ia. The product is reduced to give a compound of formulaIb. |
