PHENYL OR PHENOXY SUBSTITUTED SPIRO-IMIDAZOLIDINEDIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF AND PROCESS FOR THEIR PREPARATION

摘要

Novel phenyl or phenoxy substituted spiro-imidazolidinedione derivatives useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. The derivatives include the phenyl or phenoxy substituted spiro-imidazolidine naphthalene, chroman, thiochroman sulfoxychroman, sulfonochroman dione compounds and the substituted forms thereof.