发明名称 |
4-PREGNENE-DERIVATIVES,THEIR PREPARATION AND USE |
摘要 |
The invention refers to compounds having anti-inflammatory activity, characterized by the formula <IMAGE> (I) in the form of a stereoisomeric mixture or an epimer of the R or S type regarding the orientation of the substituents at the carbon atom in position 22, in which formula A is n-propyl or n-butyl and Z is hydroxyl or hydroxyl esterified with a fatty acid with a straight or branched hydrocarbon chain having 1-5 carbon atoms. The invention also refers to a process for the preparation of these compounds, a pharmaceutical preparation containing one of the compounds and a method for the treatment and control of inflammatory conditions. |
申请公布号 |
ZA8107772(B) |
申请公布日期 |
1982.08.25 |
申请号 |
ZA19810007772 |
申请日期 |
1981.11.10 |
申请人 |
DRACO AB |
发明人 |
THALEN BROR ARNE;BRATTSAND RALPH LENNART |
分类号 |
C07J5/00;A61K31/573;A61K31/58;A61P29/00;C07J71/00 |
主分类号 |
C07J5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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