| 摘要 |
7 beta -Acylamino-3-cephem-4-carboxylic acids substituted in the 3-position with a bis-tetrazolemethylthiomethyl group and the corresponding 7 alpha -methoxy cephalosporins represented by the formula <IMAGE> wherein R is an acyl group, R2 is H or OCH3 and R4 is H or C1-C3 alkyl; are broad spectrum antibiotics useful in the treatment and control of microorganisms pathogenic to man and animals. 7 beta -Amino nucleus compounds represented when R is hydrogen are intermediates useful in the preparation of the antibiotics where R is acyl.
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