摘要 |
<p>Nucleoside analogues having a ring-open structure of general formula <CHEM> where R and R min may be hydrogen, silyl, substituted alkyl or benzyl, and X is an optionally substituted base such as guanine or adenine, have been shown to exhibit anti-viral and other biological activities at non-toxic levels. Many phosphate-linked dinucleotides thereof are also novel compounds.</p> |