| 摘要 |
<p>RAN 4008/299 Compounds of formula I wherein X and Y each are hydrogen, halogen having an atomic number not greater than 35 or trifluoromethyl and n is 0 or 1, can be prepared by a novel process which comprises treating a compound of the general formula II wherein X and Y are as above and Z represents a hydroxyamino, amino or protected amino group with a mercuric salt under acidic conditions or with a strong acid in the presence of water, if Z is a protected amino group, splitting off the protecting group and, if a compound of formula I wherein n is O is obtained, oxidizing this compound, if desired, to a compound of formula I, wherein n is 1. The compounds of formula I are useful as intermediates in the production of pharmacologically active 2-benzazepine derivatives. The starting materials of formula II and certain pre-starting materials for their production and intermediates in the above process are also novel.</p> |
