| 发明名称 |
METHOD FOR PRODUCING 6,7-DIMETHOXY-4-AMINO- 2-/4-(2-FUROYL)-1-PIPERAZINYL/ QUINAZOLINE HYDROCHLORIDE HAVING AN ANTIHYPERTENSIVE EFFECT |
| 摘要 |
<p>of the disclosure An improved method is disclosed for producing antihypertensively active 6,7-dimethoxy-4-amino-2-¢4-(2-furoyl)-1-piperazinyl! quinazoline hydrochloride, viz. prazosine hydrochloride, by reacting methyl-N-(3,4-dimethoxy-6-cyano-phenyl)-¢4-(2-furoyl)-1-piperazinyl!thioformamidate with a large excess of ammonium chloride.</p> |
| 申请公布号 |
CA1128945(A) |
申请公布日期 |
1982.08.03 |
| 申请号 |
CA19800343361 |
申请日期 |
1980.01.09 |
| 申请人 |
ORION-YHTYMAE OY |
发明人 |
HONKANEN, ERKKI J.;PIPPURI, AINO K.;KAIRISALO, PEKKA J.;THALER, HEINRICH;KOIVISTO, MAIJA K.;TUOMI, SIRPA A. |
| 分类号 |
C07D307/68;A61K;A61K31/34;A61K31/495;A61K31/496;A61K31/505;A61K31/517;A61P9/12;C07D;C07D239/84;C07D405/12;C07D405/14;C07D407/14;(IPC1-7):07D405/14 |
主分类号 |
C07D307/68 |
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